Fear What's Inside

Based on Jeff VanderMeer's best-selling Southern Reach Trilogy, ANNIHILATION stars Natalie Portman, Jennifer Jason Leigh, Gina Rodriguez, Tessa Thompson, Tuva Novotny and Oscar Isaac. It was written and directed by Alex Garland (Ex Machina, 28 Days Later).

  • 1 hr 55 minChildren under 17 may not attend R-rated movies unaccompanied by a parent or adult guardian. Children ages 6 and under are not allowed at R-rated movies after 6pm.RHDSD
  • Feb 23, 2018
  • Science Fiction

More Trailers and Videos for Annihilation

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2018 Breakout Sci-Fi Hit?

The sci-fi thriller Annihilation hits theaters in late February, and it looks to be truly special.

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Hear From the Female-Led Cast

In an AMC exclusive interview, the stars of ANNIHILATION discussed their dynamic, yet self-destructive characters and how director Alex Garland adapted the novel of the same name for the big screen.

Cast & Crew

  • Natalie PortmanLena

  • Oscar IsaacKane

  • Tessa ThompsonJosie Radek

  • Jennifer Jason LeighDr. Ventress

  • Gina RodriguezAnya Thorensen

  • Sonoya MizunoHumanoid & Katie (Med Student)

  • Alex GarlandDirector

  • Allon ReichProducer

  • Andrew MacDonaldProducer

  • Alex GarlandWriter