Lisa Reisert (Rachel McAdams) hates to fly, but the terror that awaits her on the night flight to Miami has nothing to do with a fear of flying. Moments after takeoff, Lisa's seatmate, Jackson (Cillian Murphy), menacingly reveals the real reason he's on board: He is an operative in a plot to kill a rich and powerful businessman... and Lisa is the key to its success. If she refuses to cooperate, her own father will be killed by an assassin awaiting a call from Jackson.
